You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on Livestock Metabolome Database.
Record Information
Version1.0
Creation Date2016-07-13 19:41:59 UTC
Update Date2021-04-30 20:57:58 UTC
LmdbLMDB00083
Secondary Accession NumbersNone
Metabolite Identification
Common NameL-Serine
DescriptionSerine is a nonessential amino acid derived from glycine. Like all the amino acid building blocks of protein and peptides, serine can become essential under certain conditions, and is thus important in maintaining health and preventing disease. Low-average concentration of serine compared to other amino acids is found in muscle. Serine is highly concentrated in all cell membranes. (http://www.dcnutrition.com/AminoAcids/) L-Serine may be derived from four possible sources: dietary intake; biosynthesis from the glycolytic intermediate 3-phosphoglycerate; from glycine ; and by protein and phospholipid degradation. Little data is available on the relative contributions of each of these four sources of l-serine to serine homoeostasis. It is very likely that the predominant source of l-serine will be very different in different tissues and during different stages of animal development. In the biosynthetic pathway, the glycolytic intermediate 3-phosphoglycerate is converted into phosphohydroxypyruvate, in a reaction catalyzed by 3-phosphoglycerate dehydrogenase (3- PGDH; EC 1.1.1.95). Phosphohydroxypyruvate is metabolized to phosphoserine by phosphohydroxypyruvate aminotransferase (EC 2.6.1.52) and, finally, phosphoserine is converted into l-serine by phosphoserine phosphatase (PSP; EC 3.1.3.3). In liver tissue, the serine biosynthetic pathway is regulated in response to dietary and hormonal changes. Of the three synthetic enzymes, the properties of 3-PGDH and PSP are the best documented. Hormonal factors such as glucagon and corticosteroids also influence 3-PGDH and PSP activities in interactions dependent upon the diet. L-serine plays a central role in cellular proliferation. L-Serine is the predominant source of one-carbon groups for the de novo synthesis of purine nucleotides and deoxythymidine monophosphate. It has long been recognized that, in cell cultures, L-serine is a conditional essential amino acid, because it cannot be synthesized in sufficient quantities to meet the cellular demands for its utilization. In recent years, L-serine and the products of its metabolism have been recognized not only to be essential for cell proliferation, but also to be necessary for specific functions in the central nervous system. The findings of altered levels of serine and glycine in patients with psychiatric disorders and the severe neurological abnormalities in patients with defects of L-serine synthesis underscore the importance of L-serine in brain development and function. (PMID 12534373 ).
Structure
Thumb
Synonyms
ValueSource
(2S)-2-Amino-3-hydroxypropanoic acidChEBI
(S)-(-)-SerineChEBI
(S)-2-Amino-3-hydroxypropanoic acidChEBI
(S)-alpha-Amino-beta-hydroxypropionic acidChEBI
(S)-SerineChEBI
beta-Hydroxy-L-alanineChEBI
beta-HydroxyalanineChEBI
L-(-)-SerineChEBI
L-2-Amino-3-hydroxypropionic acidChEBI
L-3-Hydroxy-2-aminopropionic acidChEBI
L-3-Hydroxy-alanineChEBI
L-SerChEBI
L-SerinChEBI
SChEBI
SerChEBI
SERINEChEBI
(2S)-2-Amino-3-hydroxypropanoateGenerator
(S)-2-Amino-3-hydroxypropanoateGenerator
(S)-a-Amino-b-hydroxypropionateGenerator
(S)-a-Amino-b-hydroxypropionic acidGenerator
(S)-alpha-Amino-beta-hydroxypropionateGenerator
(S)-Α-amino-β-hydroxypropionateGenerator
(S)-Α-amino-β-hydroxypropionic acidGenerator
b-Hydroxy-L-alanineGenerator
Β-hydroxy-L-alanineGenerator
b-HydroxyalanineGenerator
Β-hydroxyalanineGenerator
L-2-Amino-3-hydroxypropionateGenerator
L-3-Hydroxy-2-aminopropionateGenerator
(-)-SerineHMDB
(S)-2-Amino-3-hydroxy-propanoateHMDB
(S)-2-Amino-3-hydroxy-propanoic acidHMDB
(S)-b-Amino-3-hydroxypropionateHMDB
(S)-b-Amino-3-hydroxypropionic acidHMDB
(S)-beta-Amino-3-hydroxypropionateHMDB
(S)-beta-Amino-3-hydroxypropionic acidHMDB
2-Amino-3-hydroxypropanoateHMDB
2-Amino-3-hydroxypropanoic acidHMDB
3-Hydroxy-L-alanineHMDB
L SerineHMDB
(3R,3'r,6S)-4,5-DIDEHYDRO-5,6-dihydro-BETA,BETA-carotene-3,3'-diolHMDB
Bo-xanHMDB
e 161bHMDB
XanthophyllHMDB
(3R,3'r,6S)-4,5-DIDEHYDRO-5,6-dihydro-b,b-carotene-3,3'-diolHMDB
(3R,3'r,6S)-4,5-DIDEHYDRO-5,6-dihydro-β,β-carotene-3,3'-diolHMDB
Chemical FormulaC3H7NO3
Average Molecular Weight105.0926
Monoisotopic Molecular Weight105.042593095
IUPAC Name(2S)-2-amino-3-hydroxypropanoic acid
Traditional NameL-serine
CAS Registry Number56-45-1
SMILES
N[C@@H](CO)C(O)=O
InChI Identifier
InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1
InChI KeyMTCFGRXMJLQNBG-REOHCLBHSA-N
Chemical Taxonomy
Description belongs to the class of organic compounds known as serine and derivatives. Serine and derivatives are compounds containing serine or a derivative thereof resulting from reaction of serine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
KingdomOrganic compounds
Super ClassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
Sub ClassAmino acids, peptides, and analogues
Direct ParentSerine and derivatives
Alternative Parents
Substituents
  • Serine or derivatives
  • Alpha-amino acid
  • L-alpha-amino acid
  • Beta-hydroxy acid
  • Hydroxy acid
  • Amino acid
  • Carboxylic acid
  • Monocarboxylic acid or derivatives
  • Alcohol
  • Primary amine
  • Primary alcohol
  • Organooxygen compound
  • Organonitrogen compound
  • Hydrocarbon derivative
  • Primary aliphatic amine
  • Organic oxide
  • Organopnictogen compound
  • Carbonyl group
  • Organic oxygen compound
  • Amine
  • Organic nitrogen compound
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External Descriptors
Ontology
StatusDetected and Quantified
OriginNot Available
BiofunctionNot Available
ApplicationNot Available
Cellular locationsNot Available
Physical Properties
StateNot Available
Experimental Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Predicted Properties
PropertyValueSource
logP-3.4ALOGPS
logP-3.9ChemAxon
logS0.66ALOGPS
pKa (Strongest Acidic)2.03ChemAxon
pKa (Strongest Basic)8.93ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count3ChemAxon
Polar Surface Area83.55 ŲChemAxon
Rotatable Bond Count2ChemAxon
Refractivity22.04 m³·mol⁻¹ChemAxon
Polarizability9.39 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyView
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS)splash10-0udi-0940000000-59d5e0f76fd204be8110Spectrum
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS)splash10-0udi-0980000000-ab49fc3ee88db87d1a16Spectrum
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (2 TMS)splash10-0159-0900000000-8e169037bcbe1dcd5de8Spectrum
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS)splash10-0uxr-0970000000-67271ed235e35c662db5Spectrum
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS)splash10-00di-9540000000-1297bf302358bcf0f1c0Spectrum
GC-MSGC-MS Spectrum - GC-MS (3 TMS)splash10-0uxr-1790000000-caaa37778f5a4686f5f0Spectrum
GC-MSGC-MS Spectrum - EI-B (Non-derivatized)splash10-0159-0900000000-ae4f860052c41e9ba734Spectrum
GC-MSGC-MS Spectrum - EI-B (Non-derivatized)splash10-0uxr-0590000000-ce32a8bfb64d16590b52Spectrum
GC-MSGC-MS Spectrum - GC-EI-TOF (Non-derivatized)splash10-0udi-0940000000-59d5e0f76fd204be8110Spectrum
GC-MSGC-MS Spectrum - GC-EI-TOF (Non-derivatized)splash10-0udi-0980000000-ab49fc3ee88db87d1a16Spectrum
GC-MSGC-MS Spectrum - GC-EI-TOF (Non-derivatized)splash10-0159-0900000000-8e169037bcbe1dcd5de8Spectrum
GC-MSGC-MS Spectrum - GC-EI-TOF (Non-derivatized)splash10-0uxr-0970000000-67271ed235e35c662db5Spectrum
GC-MSGC-MS Spectrum - GC-EI-QQ (Non-derivatized)splash10-00dr-7966000000-7b5b37fd4ac885548172Spectrum
GC-MSGC-MS Spectrum - GC-EI-TOF (Non-derivatized)splash10-00di-9540000000-1297bf302358bcf0f1c0Spectrum
GC-MSGC-MS Spectrum - GC-MS (Non-derivatized)splash10-0uxr-1790000000-caaa37778f5a4686f5f0Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positivesplash10-06sl-9000000000-033631650075b940e0e2Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (2 TMS) - 70eV, Positivesplash10-0fkl-9420000000-ed7a327e1f071802a4ddSpectrum
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, PositiveNot AvailableSpectrum
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, PositiveNot AvailableSpectrum
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (TMS_1_1) - 70eV, PositiveNot AvailableSpectrum
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (TMS_1_2) - 70eV, PositiveNot AvailableSpectrum
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (TMS_1_3) - 70eV, PositiveNot AvailableSpectrum
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (TMS_2_2) - 70eV, PositiveNot AvailableSpectrum
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (TMS_2_3) - 70eV, PositiveNot AvailableSpectrum
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (TMS_2_4) - 70eV, PositiveNot AvailableSpectrum
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)splash10-03di-9100000000-38f84912ebfc7b4e8339Spectrum
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)splash10-03dl-9000000000-89e57995d3ca765a20e8Spectrum
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)splash10-01ox-9100000000-f3baf93032cc9f09cf2dSpectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positivesplash10-0zfr-0900000000-b6085e53e881cdaa1824Spectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positivesplash10-000i-9000000000-2e16e9d6f9b3c2688f8aSpectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positivesplash10-0a4i-9000000000-9857daa028fb3016a7e2Spectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positivesplash10-0006-0009200000-0617acd25c69bf24ad1fSpectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positivesplash10-0a4i-0900000000-823dfcf6229956372e31Spectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positivesplash10-0a4i-9000000000-eec63565f8a9fe4bd336Spectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positivesplash10-000i-9000000000-008412efd202c202d56aSpectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positivesplash10-0002-0930000000-932aedc4efb5e1dd5e7bSpectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negativesplash10-0w29-0951000000-cd0895e475dd50e4934dSpectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negativesplash10-00di-9000000000-15294ba22b153cf5ab5bSpectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negativesplash10-014i-9000000000-48c370acff657443f0e6Spectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negativesplash10-0udi-0190000000-1bad10ba7388ce0c2249Spectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negativesplash10-0ue9-0792100000-9f2bfe40e4c01044d209Spectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negativesplash10-00di-9000000000-dfa7aca58cc28303ebc7Spectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negativesplash10-0udi-0900000000-282f31d8021649afdbe8Spectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negativesplash10-0udi-0290000000-eeee98e6b0514b08cd63Spectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Negativesplash10-0udi-1900000000-ed66566e27a94ee99f13Spectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Negativesplash10-00di-9100000000-b9f6b4b6ee7c88a9c569Spectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Negativesplash10-00di-9000000000-929aea63ace0e20c6d43Spectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Negativesplash10-00di-9000000000-ba9cd5b3e37ded5d3764Spectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Positivesplash10-0a4i-6900000000-5622633ab0a27d2e5360Spectrum
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Positivesplash10-03di-9000000000-3e25ca80e2e62be19ac5Spectrum
MSMass Spectrum (Electron Ionization)splash10-0200-9000000000-dc5e2afcfab602641180Spectrum
1D NMR1H NMR SpectrumNot AvailableSpectrum
1D NMR13C NMR SpectrumNot AvailableSpectrum
1D NMR1H NMR SpectrumNot AvailableSpectrum
1D NMR13C NMR SpectrumNot AvailableSpectrum
1D NMR1H NMR SpectrumNot AvailableSpectrum
1D NMR13C NMR SpectrumNot AvailableSpectrum
1D NMR1H NMR SpectrumNot AvailableSpectrum
1D NMR13C NMR SpectrumNot AvailableSpectrum
1D NMR1H NMR SpectrumNot AvailableSpectrum
1D NMR13C NMR SpectrumNot AvailableSpectrum
1D NMR1H NMR SpectrumNot AvailableSpectrum
1D NMR13C NMR SpectrumNot AvailableSpectrum
1D NMR1H NMR SpectrumNot AvailableSpectrum
1D NMR13C NMR SpectrumNot AvailableSpectrum
1D NMR1H NMR SpectrumNot AvailableSpectrum
1D NMR13C NMR SpectrumNot AvailableSpectrum
1D NMR1H NMR SpectrumNot AvailableSpectrum
1D NMR13C NMR SpectrumNot AvailableSpectrum
1D NMR1H NMR SpectrumNot AvailableSpectrum
1D NMR13C NMR SpectrumNot AvailableSpectrum
1D NMR1H NMR SpectrumNot AvailableSpectrum
2D NMR[1H,1H] 2D NMR SpectrumNot AvailableSpectrum
2D NMR[1H,13C] 2D NMR SpectrumNot AvailableSpectrum
Biological Properties
Cellular LocationsNot Available
Biofluid Locations and Tissue Locations
  • Cerebrospinal Fluid (CSF)
  • Colostrum
  • Embryo culture media
  • Feces
  • Follicular Fluid
  • Kidney
  • Lung
  • Meat
  • Milk
  • Plasma
  • Ruminal Fluid
  • Serum
  • Synovial Fluid
  • Urine
Concentrations
BiofluidStatusValueConditionSpeciesReferenceDetails
Cerebrospinal Fluid (CSF)Detected but not QuantifiedNot ApplicableNot AvailableOvine details
ColostrumDetected but not QuantifiedNot ApplicableNot AvailableBovine details
ColostrumDetected but not QuantifiedNot ApplicableNot AvailableBovine details
Embryo culture mediaDetected but not QuantifiedNot ApplicableNot AvailableBovine details
Embryo culture mediaDetected but not QuantifiedNot ApplicableNot AvailableBovine details
FecesDetected but not QuantifiedNot ApplicableNot AvailableOvine details
FecesDetected but not QuantifiedNot ApplicableNot AvailableEquine
    • E. E. Escalona, J...
details
Follicular FluidDetected and Quantified120 +/- 10-160+/-0 uMNot AvailablePorcine details
KidneyDetected but not QuantifiedNot ApplicableNot AvailablePorcine details
LungDetected but not QuantifiedNot ApplicableNot AvailablePorcine details
MeatDetected but not QuantifiedNot ApplicableNot AvailableBovine details
MeatDetected but not QuantifiedNot ApplicableNot AvailableBovine details
MilkDetected but not QuantifiedNot ApplicableNot AvailableBovine details
PlasmaDetected and Quantified148 +/- 3-159+/-8 uMNot AvailablePorcine details
PlasmaDetected and Quantified424 +/- 18-450+/-65 uMNot AvailablePorcine details
PlasmaDetected and Quantified478 +/- 49-347+/-35 uMNot AvailablePorcine details
PlasmaDetected and Quantified58.4 uMNot AvailableBovine details
PlasmaDetected and Quantified61.5 uMNot AvailableBovine details
PlasmaDetected and Quantified66.7 uMNot AvailableBovine details
PlasmaDetected and Quantified72.0-112.3 uMNot AvailableOvine details
PlasmaDetected and Quantified80.0 +/- 20.8 uMNot AvailableOvine details
PlasmaDetected but not QuantifiedNot ApplicableNot AvailableBovine details
PlasmaDetected but not QuantifiedNot ApplicableNot AvailableOvine details
PlasmaDetected but not QuantifiedNot ApplicableNot AvailableOvine details
PlasmaDetected but not QuantifiedNot ApplicableNot AvailablePorcine details
PlasmaDetected but not QuantifiedNot ApplicableNot AvailableBovine details
PlasmaDetected but not QuantifiedNot ApplicableNot AvailablePorcine details
PlasmaDetected and Quantified130.32 uMNot AvailablePorcine details
PlasmaDetected and Quantified146.02 uMNot AvailablePorcine details
PlasmaDetected and Quantified148.99 uMNot AvailablePorcine details
PlasmaDetected and Quantified170.2 uMNot AvailablePorcine details
Ruminal FluidDetected and Quantified123 +/- 57 uMNot AvailableBovine
    • Saleem F, Bouatra...
details
Ruminal FluidDetected and Quantified49 +/- 25 uMNot AvailableBovine
    • Saleem F, Bouatra...
details
Ruminal FluidDetected and Quantified49 +/- 25 uMNot AvailableBovine
    • Saleem F, Bouatra...
details
Ruminal FluidDetected and Quantified50 +/- 14 uMNot AvailableBovine
    • Saleem F, Bouatra...
details
Ruminal FluidDetected and Quantified85 +/- 29 uMNot AvailableBovine
    • Saleem F, Bouatra...
details
Ruminal FluidDetected but not QuantifiedNot ApplicableNot AvailableBovine
    • Fozia Saleem, Sou...
details
SerumDetected and Quantified77.9116 +/- 19.264 uM
Normal
Ovine
    • Goldansaz et al.,...
details
SerumDetected and Quantified95.3831 +/- 27.8633 uM
Normal
Ovine
    • Goldansaz et al.,...
details
SerumDetected and Quantified69.1625 +/- 18.4306 uM
Normal
Ovine
    • Goldansaz et al.,...
details
SerumDetected and Quantified176.4 uMNot AvailablePorcine
    • Barbara U. Metzle...
details
SerumDetected and Quantified85.4119 +/- 40.6463 uM
Normal
Ovine
    • Goldansaz et al.,...
details
SerumDetected and Quantified216.4 uMNot AvailablePorcine
    • Barbara U. Metzle...
details
SerumDetected and Quantified232.8 uMNot AvailablePorcine
    • Barbara U. Metzle...
details
SerumDetected and Quantified250.3 uMNot AvailablePorcine
    • Barbara U. Metzle...
details
SerumDetected and Quantified59.69 +/- 22.08 uMNot AvailableOvine
    • Candidate serum m...
details
SerumDetected and Quantified70.8131 +/- 27.6125 uM
Normal
Ovine
    • Goldansaz et al.,...
details
SerumDetected and Quantified85.005 +/- 44.5437 uM
Normal
Ovine
    • Goldansaz et al.,...
details
SerumDetected and Quantified56.9293 +/- 9.9572 uM
Normal
Ovine
    • Goldansaz et al.,...
details
SerumDetected and Quantified90.823 +/- 41.9471 uM
Normal
Ovine
    • Goldansaz et al.,...
details
SerumDetected and Quantified108 uMNot AvailablePorcine details
SerumDetected and Quantified82.594 uMNot AvailablePorcine details
SerumDetected and Quantified83.545 uMNot AvailablePorcine details
SerumDetected and Quantified120.275 uMNot AvailablePorcine details
SerumDetected and Quantified74.2919 +/- 24.3682 uM
Normal
Ovine
    • Goldansaz et al.,...
details
SerumDetected and Quantified76.9167 +/- 34.6393 uM
Normal
Ovine
    • Goldansaz et al.,...
details
SerumDetected and Quantified101.3859 +/- 48.4164 uM
Normal
Ovine
    • Goldansaz et al.,...
details
SerumDetected but not QuantifiedNot ApplicableNot AvailablePorcine details
SerumDetected but not QuantifiedNot ApplicableNot AvailableBovine details
SerumDetected but not QuantifiedNot ApplicableNot AvailableBovine details
SerumDetected but not QuantifiedNot ApplicableNot AvailableBovine details
SerumDetected and Quantified86.0713 +/- 31.5363 uM
Normal
Ovine
    • Goldansaz et al.,...
details
SerumDetected and Quantified78.9266 +/- 33.6965 uM
Normal
Ovine
    • Goldansaz et al.,...
details
SerumDetected and Quantified130 +/- 10 uMNot AvailablePorcine details
SerumDetected and Quantified83.9399 +/- 34.2627 uM
Normal
Ovine
    • Goldansaz et al.,...
details
SerumDetected and Quantified64.5691 +/- 16.7731 uM
Normal
Ovine
    • Goldansaz et al.,...
details
SerumDetected and Quantified77.7974 +/- 23.844 uM
Normal
Ovine
    • Goldansaz et al.,...
details
SerumDetected and Quantified97.3293 +/- 54.9106 uM
Normal
Ovine
    • Goldansaz et al.,...
details
SerumDetected and Quantified58.3827 +/- 16.962 uM
Normal
Ovine
    • Goldansaz et al.,...
details
SerumDetected and Quantified78.1192 +/- 40.1132 uM
Normal
Ovine
    • Goldansaz et al.,...
details
SerumDetected and Quantified81.9694 +/- 41.3794 uM
Normal
Ovine
    • Goldansaz et al.,...
details
Synovial FluidDetected but not QuantifiedNot ApplicableNot AvailableOvine details
UrineDetected but not QuantifiedNot ApplicableNot AvailableEquine
    • E. E. Escalona, J...
details
DrugBank IDDB00133
HMDB IDHMDB0000187
FooDB IDFDB012739
Phenol Explorer IDNot Available
KNApSAcK IDC00001393
BiGG ID33717
BioCyc IDSER
METLIN ID5203
PDB IDNot Available
Wikipedia LinkL-serine
Chemspider ID5736
ChEBI ID17115
PubChem Compound ID5951
Kegg Compound IDC00065
YMDB IDYMDB00112
ECMDB IDECMDB00187
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General References
  1. de Koning TJ, Snell K, Duran M, Berger R, Poll-The BT, Surtees R: L-serine in disease and development. Biochem J. 2003 May 1;371(Pt 3):653-61. [12534373 ]