Livestock Metabolome Database: Showing metabocard for L-Lactic acid (LMDB00084)

Identification Taxonomy Ontology Physical properties Spectra Biological properties Concentrations Links References XML

Record Information

Version

1.0

Creation Date

2016-07-13 19:42:01 UTC

Update Date

2021-04-30 20:57:58 UTC

Lmdb

LMDB00084

Secondary Accession Numbers

None

Metabolite Identification

Common Name

L-Lactic acid

Description

Lactic acid plays a role in several biochemical processes and is produced in the muscles during intense activity. Lactate measurement in the critically ill has been traditionally used to stratify patients with poor outcome. However, plasma lactate levels are the result of a finely tuned interplay of factors that affect the balance between its production and its clearance. When the oxygen supply does not match its consumption, organisms such as man who are forced to produce ATP for their integrity adapt in many different ways up to the point when energy failure occurs. Lactate, being part of the adaptive response, may then be used to assess the severity of the supply/demand imbalance. In such a scenario, the time to intervention becomes relevant: early and effective treatment may allow the cell to revert to a normal state, as long as the oxygen machinery (i.e. mitochondria) is intact. Conversely, once the mitochondria are deranged, energy failure occurs even in the presence of normoxia. The lactate increase in critically ill patients may therefore be viewed as an early marker of a potentially reversible state. (PMID 16356243 ) A number of studies have demonstrated that malignant transformation is associated with an increase in glycolytic flux and in anaerobic and aerobic cellular lactate excretion. Using quantitative bioluminescence imaging in various primary carcinomas in patients (uterine cervix, head and neck, colorectal region) at first diagnosis of the disease, lactate concentrations in tumors in vivo could be relatively low or extremely high (up to 40 micromol/g) in different individual tumors or within the same lesion. In all tumor entities investigated, high molar concentrations of lactate were correlated with a high incidence of distant metastasis already in an early stage of the disease. Low lactate tumors (< median of approximately 8 micromol/g) were associated with both a longer overall and disease free survival compared to high lactate lesions (lactate > approximately 8 micromol/g). Lactate dehydrogenase was found to be upregulated in most of these tumors compared to surrounding normal tissue. (PMID 15279558 ).

Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
(-)-Lactic acid	ChEBI
(R)-(-)-Lactic acid	ChEBI
D-2-Hydroxypropanoic acid	ChEBI
D-2-Hydroxypropionic acid	ChEBI
D-Milchsaeure	ChEBI
LACTIC ACID	ChEBI
D-Lactate	Kegg
(-)-Lactate	Generator
(R)-(-)-Lactate	Generator
D-2-Hydroxypropanoate	Generator
D-2-Hydroxypropionate	Generator
LACTate	Generator
L-Lactate	HMDB
(R)-2-Hydroxypropanoate	HMDB
(R)-2-Hydroxypropanoic acid	HMDB
(R)-2-Hydroxypropionate	HMDB
(R)-2-Hydroxypropionic acid	HMDB
(R)-a-Hydroxypropionate	HMDB
(R)-a-Hydroxypropionic acid	HMDB
(R)-alpha-Hydroxypropionate	HMDB
(R)-alpha-Hydroxypropionic acid	HMDB
(R)-Lactate	HMDB
(R)-Lactic acid	HMDB
D-(-)-Lactate	HMDB
D-(-)-Lactic acid	HMDB
delta-(-)-Lactate	HMDB
delta-(-)-Lactic acid	HMDB
delta-2-Hydroxypropanoate	HMDB
delta-2-Hydroxypropanoic acid	HMDB
delta-2-Hydroxypropionate	HMDB
delta-2-Hydroxypropionic acid	HMDB
delta-Lactate	HMDB
delta-Lactic acid	HMDB
DLA	HMDB
L-(+)-Lactate	HMDB
Propel	HMDB
Tisulac	HMDB
2 Hydroxypropanoic acid	HMDB
2 Hydroxypropionic acid	HMDB
2-Hydroxypropanoic acid	HMDB
Ammonium lactate	HMDB
L Lactic acid	HMDB
2-Hydroxypropionic acid	HMDB
Sarcolactic acid	HMDB
D Lactic acid	HMDB
Lactate, ammonium	HMDB
L-Lactic acid	HMDB
D-Lactic acid	ChEBI

Chemical Formula

C₃H₆O₃

Average Molecular Weight

90.0779

Monoisotopic Molecular Weight

90.031694058

IUPAC Name

(2R)-2-hydroxypropanoic acid

Traditional Name

D-lactic acid

CAS Registry Number

79-33-4

SMILES

C[C@H](O)C(O)=O

InChI Identifier

InChI=1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1

InChI Key

JVTAAEKCZFNVCJ-REOHCLBHSA-N

Chemical Taxonomy

Description

belongs to the class of organic compounds known as alpha hydroxy acids and derivatives. These are organic compounds containing a carboxylic acid substituted with a hydroxyl group on the adjacent carbon.

Kingdom

Organic compounds

Super Class

Organic acids and derivatives

Class

Hydroxy acids and derivatives

Sub Class

Alpha hydroxy acids and derivatives

Direct Parent

Alpha hydroxy acids and derivatives

Alternative Parents

Substituents

Alpha-hydroxy acid
Secondary alcohol
Monocarboxylic acid or derivatives
Carboxylic acid
Carboxylic acid derivative
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Alcohol
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

2-hydroxypropanoic acid (CHEBI:42111 )

Ontology

Status

Detected and Quantified

Origin

Not Available

Biofunction

Not Available

Application

Not Available

Cellular locations

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	-0.79	ALOGPS
logP	-0.47	ChemAxon
logS	0.79	ALOGPS
pKa (Strongest Acidic)	3.78	ChemAxon
pKa (Strongest Basic)	-3.7	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	3	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	57.53 Å²	ChemAxon
Rotatable Bond Count	1	ChemAxon
Refractivity	18.84 m³·mol⁻¹	ChemAxon
Polarizability	8.05 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	Yes	ChemAxon
MDDR-like Rule	Yes	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	View
GC-MS	GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (Non-derivatized)	splash10-00kb-0900000000-fb59ec16914501aa19ab	Spectrum
GC-MS	GC-MS Spectrum - EI-B (Non-derivatized)	splash10-014j-0900000000-c4d9e12b4b0150eda54b	Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Non-derivatized)	splash10-00kb-0900000000-fb59ec16914501aa19ab	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	splash10-0006-9000000000-a3691f383d440fb00e1f	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (2 TMS) - 70eV, Positive	splash10-01b9-9620000000-f7faa7db9c1be3d9d975	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	Not Available	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 10V, Negative (Annotated)	splash10-000i-9000000000-704f8ff33156c82a02d1	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 25V, Negative (Annotated)	splash10-000m-9000000000-023931446d9bb3330e7f	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 40V, Negative (Annotated)	splash10-000l-9000000000-0fb29afb128baea2240b	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-IT , negative	splash10-000i-9000000000-d7cd347946e49a57860e	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 40V, Negative	splash10-0006-9000000000-aee01e43e8ee93db755d	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 10V, Negative	splash10-000f-9000000000-581a00222505e9e4b458	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - 20V, Negative	splash10-0006-9000000000-5bfd9fdf1c0df2054452	Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-006x-9000000000-5f417f4a6d08f0ab00ed	Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-00dm-9000000000-df7a94bb1a9cf6e78e1a	Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-004j-9000000000-dc2a1b965287b9dfee9c	Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-000i-9000000000-c3686a681cc9bbf039e1	Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-000i-9000000000-ddad20647c2ac56efd22	Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-00di-9000000000-b728b45617afcc6b67da	Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-000i-9000000000-b586cb8f053eb4465b4e	Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-000i-9000000000-400a5f1c0dfcc32ef2bb	Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-0007-9000000000-ad5eb77c7e0a96f3a40a	Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-0002-9000000000-00ba25458eb6c0cc2940	Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-0002-9000000000-00ba25458eb6c0cc2940	Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-0002-9000000000-00ba25458eb6c0cc2940	Spectrum
MS	Mass Spectrum (Electron Ionization)	splash10-002b-9000000000-50213d6b39ef9741c466	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
2D NMR	[1H,1H] 2D NMR Spectrum	Not Available	Spectrum
2D NMR	[1H,13C] 2D NMR Spectrum	Not Available	Spectrum

Biological Properties

Cellular Locations

Not Available

Biofluid Locations and Tissue Locations

Brain
Cerebrospinal Fluid (CSF)
Colostrum
Feces
Follicular Fluid
Jejunum
Kidney
Kidney perfusate
Liver
Lung
Meat
Milk
Plasma
Rumen
Ruminal Fluid
Serum
Synovial Fluid
Urine
Vitreous Humour

Concentrations

Biofluid	Status	Value	Condition	Species	Reference	Details
Brain	Detected but not Quantified	Not Applicable	Not Available	Ovine	25959287	details
Cerebrospinal Fluid (CSF)	Detected but not Quantified	Not Applicable	Not Available	Ovine	17510975	details
Cerebrospinal Fluid (CSF)	Detected but not Quantified	Not Applicable	Not Available	Ovine	17510975	details
Colostrum	Detected but not Quantified	Not Applicable	Not Available	Bovine	25637742	details
Colostrum	Detected but not Quantified	Not Applicable	Not Available	Bovine	S. F. Graham, T. ...	details
Feces	Detected but not Quantified	Not Applicable	Not Available	Equine	E. E. Escalona, J...	details
Follicular Fluid	Detected and Quantified	1420.992-10546.427 uM	Not Available	Bovine	C. Lutwak-Mann. N...	details
Jejunum	Detected but not Quantified	Not Applicable	Not Available	Porcine	21584308	details
Kidney	Detected but not Quantified	Not Applicable	Not Available	Porcine	21761043	details
Kidney perfusate	Detected but not Quantified	Not Applicable	Not Available	Porcine	25502759	details
Liver	Detected but not Quantified	Not Applicable	Not Available	Porcine	21761043	details
Lung	Detected and Quantified	1.1+/-0.11 umol/g	Not Available	Porcine	23412987	details
Meat	Detected but not Quantified	Not Applicable	Not Available	Porcine	24200563	details
Meat	Detected and Quantified	367.58+/-50.52 umol/g	Not Available	Bovine	S. F. Graham, T. ...	details
Meat	Detected and Quantified	383.14+/-51.35 umol/g	Not Available	Bovine	S. F. Graham, T. ...	details
Meat	Detected and Quantified	392.24+/-63.98 umol/g	Not Available	Bovine	S. F. Graham, T. ...	details
Meat	Detected but not Quantified	Not Applicable	Not Available	Bovine	25637742	details
Meat	Detected and Quantified	7.10+/-1.14 umol/g	Not Available	Bovine	S. F. Graham, T. ...	details
Meat	Detected and Quantified	14817.25 +/- 555.7 uM	Not Available	Bovine	20831251	details
Meat	Detected and Quantified	16764.97 +/- 482.13 uM	Not Available	Bovine	20831251	details
Meat	Detected and Quantified	17300.81 +/- 1145.11 uM	Not Available	Bovine	20831251	details
Meat	Detected but not Quantified	Not Applicable	Not Available	Bovine	S. F. Graham, T. ...	details
Meat	Detected and Quantified	21406.66 +/- 443.4 uM	Not Available	Bovine	20831251	details
Milk	Detected and Quantified	32-136 uM	Not Available	Bovine	22098372	details
Milk	Detected and Quantified	2-3538 uM	Not Available	Bovine	20338431	details
Milk	Detected but not Quantified	Not Applicable	Not Available	Bovine	23497994	details
Milk	Detected but not Quantified	Not Applicable	Not Available	Bovine	23438684	details
Milk	Detected but not Quantified	Not Applicable	Not Available	Bovine	23182357	details
Milk	Detected but not Quantified	Not Applicable	Not Available	Bovine	25108860	details
Milk	Detected but not Quantified	Not Applicable	Not Available	Bovine	25087032	details
Plasma	Detected and Quantified	5210 +/- 340-5550+/-0.00 uM	Not Available	Porcine	22513987	details
Plasma	Detected and Quantified	5310 +/- 150-5200+/-90 uM	Not Available	Porcine	22513987	details
Plasma	Detected and Quantified	5550 +/- 0-5550+/-0.00 uM	Not Available	Porcine	22513987	details
Plasma	Detected and Quantified	1420 +/- 310-6230+/-790 uM	Not Available	Porcine	22612070	details
Plasma	Detected and Quantified	1700-2900 uM	Not Available	Ovine	17900638	details
Plasma	Detected and Quantified	3490 +/- 1630 uM	Not Available	Ovine	17900638	details
Plasma	Detected and Quantified	2420 +/- 370 uM	Not Available	Bovine	Abdullah BAŞOĞLU,...	details
Plasma	Detected and Quantified	4510 +/- 1340 uM	Not Available	Bovine	Abdullah BAŞOĞLU,...	details
Plasma	Detected and Quantified	500 +/- 90 uM	Not Available	Bovine	Abdullah BAŞOĞLU,...	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Bovine	22370585	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Bovine	22370585	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Porcine	25502722	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Bovine	25913299	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Bovine	25913299	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Bovine	24440255	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Porcine	21859467	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Porcine	23100586	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Porcine	19603403	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Ovine	22242129	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Bovine	24070026	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Porcine	22673149	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Porcine	20231903	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Equine	21496096	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Bovine	Trabi M, Keller M...	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Equine	E. E. Escalona, J...	details
Rumen	Detected but not Quantified	Not Applicable	Not Available	Bovine	Hanne Christine B...	details
Ruminal Fluid	Detected and Quantified	122 uM	Not Available	Bovine	Burim NA, Qendrim...	details
Ruminal Fluid	Detected and Quantified	124 uM	Not Available	Bovine	Burim NA, Qendrim...	details
Ruminal Fluid	Detected and Quantified	133 uM	Not Available	Bovine	Burim NA, Qendrim...	details
Ruminal Fluid	Detected and Quantified	228 uM	Not Available	Bovine	Burim NA, Qendrim...	details
Ruminal Fluid	Detected and Quantified	156.9 uM	Not Available	Bovine	22959937	details
Ruminal Fluid	Detected and Quantified	173.5 uM	Not Available	Bovine	22959937	details
Ruminal Fluid	Detected and Quantified	180.4 uM	Not Available	Bovine	22959937	details
Ruminal Fluid	Detected and Quantified	282 uM	Not Available	Bovine	22959937	details
Ruminal Fluid	Detected and Quantified	123 +/- 11 uM	Not Available	Bovine	Saleem F, Bouatra...	details
Ruminal Fluid	Detected and Quantified	134 +/- 17 uM	Not Available	Bovine	Saleem F, Bouatra...	details
Ruminal Fluid	Detected and Quantified	134 +/- 17 uM	Not Available	Bovine	Saleem F, Bouatra...	details
Ruminal Fluid	Detected and Quantified	159 +/- 22 uM	Not Available	Bovine	Saleem F, Bouatra...	details
Ruminal Fluid	Detected and Quantified	180 +/- 118 uM	Not Available	Bovine	Saleem F, Bouatra...	details
Ruminal Fluid	Detected and Quantified	252 +/- 61 uM	Not Available	Bovine	Saleem F, Bouatra...	details
Ruminal Fluid	Detected and Quantified	238 +/- 14 uM	Not Available	Bovine	22706048	details
Ruminal Fluid	Detected and Quantified	331 +/- 36 uM	Not Available	Bovine	22706048	details
Ruminal Fluid	Detected and Quantified	382 +/- 39 uM	Not Available	Bovine	22706048	details
Ruminal Fluid	Detected and Quantified	290 uM	Not Available	Caprine	25471302	details
Ruminal Fluid	Detected and Quantified	350 uM	Not Available	Caprine	25471302	details
Ruminal Fluid	Detected and Quantified	440 uM	Not Available	Caprine	25471302	details
Ruminal Fluid	Detected and Quantified	1,400 +/- 160 uM	Not Available	Caprine	22706048	details
Ruminal Fluid	Detected but not Quantified	Not Applicable	Not Available	Bovine	25599412	details
Serum	Detected and Quantified	2548.644 +/- 1201.5577 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	2895.8022 +/- 1466.0911 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	2948.4762 +/- 1062.9513 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	2486.6406 +/- 1446.734 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	3292.8858 +/- 1917.8417 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	2417.0946 +/- 977.5536 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	2661.436 +/- 1829.531 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	2841.5351 +/- 1885.0176 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	3632.54 +/- 1287.97 uM	Not Available	Ovine	Candidate serum m...	details
Serum	Detected and Quantified	2431.5628 +/- 975.1355 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	2610.9589 +/- 1135.1722 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	2620.0562 +/- 1123.9173 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	2546.8599 +/- 1422.586 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	2737.1992 +/- 1023.9705 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Bovine	19275474	details
Serum	Detected and Quantified	2150.9344 +/- 1178.2859 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	2209.1038 +/- 1026.3737 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Porcine	21942754	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Porcine	18989615	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Porcine	23255817	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Porcine	26020888	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Porcine	22761248	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Porcine	21584308	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Bovine	25372282	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Bovine	25372282	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Bovine	25372282	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Porcine	21761043	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Ovine	21142080	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Porcine	21429726	details
Serum	Detected and Quantified	3098.6668 +/- 1087.5902 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	2732.7149 +/- 1355.4649 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	2694.8472 +/- 1064.072 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	2336.091 +/- 1156.0081 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Equine	Lucia Pappalardo,...	details
Serum	Detected and Quantified	3211.5212 +/- 2048.5044 uM	Normal	Ovine	Goldansaz et al.,...	details
Synovial Fluid	Detected but not Quantified	Not Applicable	Not Available	Ovine	25283885	details
Urine	Detected and Quantified	457 umol/mmol creatinine	Not Available	Porcine	23741447	details
Urine	Detected and Quantified	7946 umol/mmol creatinine	Not Available	Porcine	23741447	details
Urine	Detected but not Quantified	Not Applicable	Not Available	Porcine	21761043	details
Urine	Detected but not Quantified	Not Applicable	Not Available	Porcine	24696864	details
Urine	Detected but not Quantified	Not Applicable	Not Available	Ovine	21142080	details
Urine	Detected but not Quantified	Not Applicable	Not Available	Ovine	21142080	details
Urine	Detected but not Quantified	Not Applicable	Not Available	Equine	E. E. Escalona, J...	details
Vitreous Humour	Detected but not Quantified	Not Applicable	Not Available	Caprine	24845217	details

External Links

DrugBank ID

DB03066

HMDB ID

HMDB0001311

FooDB ID

FDB030146

Phenol Explorer ID

Not Available

KNApSAcK ID

BiGG ID

BioCyc ID

METLIN ID

PDB ID

Not Available

Wikipedia Link

Chemspider ID

ChEBI ID

PubChem Compound ID

Kegg Compound ID

YMDB ID

ECMDB ID

References

Synthesis Reference

Not Available

Material Safety Data Sheet (MSDS)

Not Available

General References

Valenza F, Aletti G, Fossali T, Chevallard G, Sacconi F, Irace M, Gattinoni L: Lactate as a marker of energy failure in critically ill patients: hypothesis. Crit Care. 2005;9(6):588-93. Epub 2005 Sep 28. [16356243 ]
Walenta S, Schroeder T, Mueller-Klieser W: Lactate in solid malignant tumors: potential basis of a metabolic classification in clinical oncology. Curr Med Chem. 2004 Aug;11(16):2195-204. [15279558 ]

Showing metabocard for L-Lactic acid (LMDB00084)

Structure for LMDB00084 (L-Lactic acid)