Livestock Metabolome Database: Showing metabocard for L-Serine (LMDB00083)

Identification Taxonomy Ontology Physical properties Spectra Biological properties Concentrations Links References XML

Record Information

Version

1.0

Creation Date

2016-07-13 19:41:59 UTC

Update Date

2021-04-30 20:57:58 UTC

Lmdb

LMDB00083

Secondary Accession Numbers

None

Metabolite Identification

Common Name

L-Serine

Description

Serine is a nonessential amino acid derived from glycine. Like all the amino acid building blocks of protein and peptides, serine can become essential under certain conditions, and is thus important in maintaining health and preventing disease. Low-average concentration of serine compared to other amino acids is found in muscle. Serine is highly concentrated in all cell membranes. (http://www.dcnutrition.com/AminoAcids/) L-Serine may be derived from four possible sources: dietary intake; biosynthesis from the glycolytic intermediate 3-phosphoglycerate; from glycine ; and by protein and phospholipid degradation. Little data is available on the relative contributions of each of these four sources of l-serine to serine homoeostasis. It is very likely that the predominant source of l-serine will be very different in different tissues and during different stages of animal development. In the biosynthetic pathway, the glycolytic intermediate 3-phosphoglycerate is converted into phosphohydroxypyruvate, in a reaction catalyzed by 3-phosphoglycerate dehydrogenase (3- PGDH; EC 1.1.1.95). Phosphohydroxypyruvate is metabolized to phosphoserine by phosphohydroxypyruvate aminotransferase (EC 2.6.1.52) and, finally, phosphoserine is converted into l-serine by phosphoserine phosphatase (PSP; EC 3.1.3.3). In liver tissue, the serine biosynthetic pathway is regulated in response to dietary and hormonal changes. Of the three synthetic enzymes, the properties of 3-PGDH and PSP are the best documented. Hormonal factors such as glucagon and corticosteroids also influence 3-PGDH and PSP activities in interactions dependent upon the diet. L-serine plays a central role in cellular proliferation. L-Serine is the predominant source of one-carbon groups for the de novo synthesis of purine nucleotides and deoxythymidine monophosphate. It has long been recognized that, in cell cultures, L-serine is a conditional essential amino acid, because it cannot be synthesized in sufficient quantities to meet the cellular demands for its utilization. In recent years, L-serine and the products of its metabolism have been recognized not only to be essential for cell proliferation, but also to be necessary for specific functions in the central nervous system. The findings of altered levels of serine and glycine in patients with psychiatric disorders and the severe neurological abnormalities in patients with defects of L-serine synthesis underscore the importance of L-serine in brain development and function. (PMID 12534373 ).

Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
(2S)-2-Amino-3-hydroxypropanoic acid	ChEBI
(S)-(-)-Serine	ChEBI
(S)-2-Amino-3-hydroxypropanoic acid	ChEBI
(S)-alpha-Amino-beta-hydroxypropionic acid	ChEBI
(S)-Serine	ChEBI
beta-Hydroxy-L-alanine	ChEBI
beta-Hydroxyalanine	ChEBI
L-(-)-Serine	ChEBI
L-2-Amino-3-hydroxypropionic acid	ChEBI
L-3-Hydroxy-2-aminopropionic acid	ChEBI
L-3-Hydroxy-alanine	ChEBI
L-Ser	ChEBI
L-Serin	ChEBI
S	ChEBI
Ser	ChEBI
SERINE	ChEBI
(2S)-2-Amino-3-hydroxypropanoate	Generator
(S)-2-Amino-3-hydroxypropanoate	Generator
(S)-a-Amino-b-hydroxypropionate	Generator
(S)-a-Amino-b-hydroxypropionic acid	Generator
(S)-alpha-Amino-beta-hydroxypropionate	Generator
(S)-Α-amino-β-hydroxypropionate	Generator
(S)-Α-amino-β-hydroxypropionic acid	Generator
b-Hydroxy-L-alanine	Generator
Β-hydroxy-L-alanine	Generator
b-Hydroxyalanine	Generator
Β-hydroxyalanine	Generator
L-2-Amino-3-hydroxypropionate	Generator
L-3-Hydroxy-2-aminopropionate	Generator
(-)-Serine	HMDB
(S)-2-Amino-3-hydroxy-propanoate	HMDB
(S)-2-Amino-3-hydroxy-propanoic acid	HMDB
(S)-b-Amino-3-hydroxypropionate	HMDB
(S)-b-Amino-3-hydroxypropionic acid	HMDB
(S)-beta-Amino-3-hydroxypropionate	HMDB
(S)-beta-Amino-3-hydroxypropionic acid	HMDB
2-Amino-3-hydroxypropanoate	HMDB
2-Amino-3-hydroxypropanoic acid	HMDB
3-Hydroxy-L-alanine	HMDB
L Serine	HMDB
(3R,3'r,6S)-4,5-DIDEHYDRO-5,6-dihydro-BETA,BETA-carotene-3,3'-diol	HMDB
Bo-xan	HMDB
e 161b	HMDB
Xanthophyll	HMDB
(3R,3'r,6S)-4,5-DIDEHYDRO-5,6-dihydro-b,b-carotene-3,3'-diol	HMDB
(3R,3'r,6S)-4,5-DIDEHYDRO-5,6-dihydro-β,β-carotene-3,3'-diol	HMDB

Chemical Formula

C₃H₇NO₃

Average Molecular Weight

105.0926

Monoisotopic Molecular Weight

105.042593095

IUPAC Name

(2S)-2-amino-3-hydroxypropanoic acid

Traditional Name

L-serine

CAS Registry Number

56-45-1

SMILES

N[C@@H](CO)C(O)=O

InChI Identifier

InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1

InChI Key

MTCFGRXMJLQNBG-REOHCLBHSA-N

Chemical Taxonomy

Description

belongs to the class of organic compounds known as serine and derivatives. Serine and derivatives are compounds containing serine or a derivative thereof resulting from reaction of serine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.

Kingdom

Organic compounds

Super Class

Organic acids and derivatives

Class

Carboxylic acids and derivatives

Sub Class

Amino acids, peptides, and analogues

Direct Parent

Serine and derivatives

Alternative Parents

Substituents

Serine or derivatives
Alpha-amino acid
L-alpha-amino acid
Beta-hydroxy acid
Hydroxy acid
Amino acid
Carboxylic acid
Monocarboxylic acid or derivatives
Alcohol
Primary amine
Primary alcohol
Organooxygen compound
Organonitrogen compound
Hydrocarbon derivative
Primary aliphatic amine
Organic oxide
Organopnictogen compound
Carbonyl group
Organic oxygen compound
Amine
Organic nitrogen compound
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

proteinogenic amino acid (CHEBI:17115 )
L-alpha-amino acid (CHEBI:17115 )
serine (CHEBI:17115 )
serine family amino acid (CHEBI:17115 )
Common amino acids (C00065 )

Ontology

Status

Detected and Quantified

Origin

Not Available

Biofunction

Not Available

Application

Not Available

Cellular locations

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	-3.4	ALOGPS
logP	-3.9	ChemAxon
logS	0.66	ALOGPS
pKa (Strongest Acidic)	2.03	ChemAxon
pKa (Strongest Basic)	8.93	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	4	ChemAxon
Hydrogen Donor Count	3	ChemAxon
Polar Surface Area	83.55 Å²	ChemAxon
Rotatable Bond Count	2	ChemAxon
Refractivity	22.04 m³·mol⁻¹	ChemAxon
Polarizability	9.39 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	Yes	ChemAxon
MDDR-like Rule	Yes	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	View
GC-MS	GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS)	splash10-0udi-0940000000-59d5e0f76fd204be8110	Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS)	splash10-0udi-0980000000-ab49fc3ee88db87d1a16	Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (2 TMS)	splash10-0159-0900000000-8e169037bcbe1dcd5de8	Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS)	splash10-0uxr-0970000000-67271ed235e35c662db5	Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS)	splash10-00di-9540000000-1297bf302358bcf0f1c0	Spectrum
GC-MS	GC-MS Spectrum - GC-MS (3 TMS)	splash10-0uxr-1790000000-caaa37778f5a4686f5f0	Spectrum
GC-MS	GC-MS Spectrum - EI-B (Non-derivatized)	splash10-0159-0900000000-ae4f860052c41e9ba734	Spectrum
GC-MS	GC-MS Spectrum - EI-B (Non-derivatized)	splash10-0uxr-0590000000-ce32a8bfb64d16590b52	Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Non-derivatized)	splash10-0udi-0940000000-59d5e0f76fd204be8110	Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Non-derivatized)	splash10-0udi-0980000000-ab49fc3ee88db87d1a16	Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Non-derivatized)	splash10-0159-0900000000-8e169037bcbe1dcd5de8	Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Non-derivatized)	splash10-0uxr-0970000000-67271ed235e35c662db5	Spectrum
GC-MS	GC-MS Spectrum - GC-EI-QQ (Non-derivatized)	splash10-00dr-7966000000-7b5b37fd4ac885548172	Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Non-derivatized)	splash10-00di-9540000000-1297bf302358bcf0f1c0	Spectrum
GC-MS	GC-MS Spectrum - GC-MS (Non-derivatized)	splash10-0uxr-1790000000-caaa37778f5a4686f5f0	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	splash10-06sl-9000000000-033631650075b940e0e2	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (2 TMS) - 70eV, Positive	splash10-0fkl-9420000000-ed7a327e1f071802a4dd	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TMS_1_1) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TMS_1_2) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TMS_1_3) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TMS_2_2) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TMS_2_3) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TMS_2_4) - 70eV, Positive	Not Available	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)	splash10-03di-9100000000-38f84912ebfc7b4e8339	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)	splash10-03dl-9000000000-89e57995d3ca765a20e8	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)	splash10-01ox-9100000000-f3baf93032cc9f09cf2d	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-0zfr-0900000000-b6085e53e881cdaa1824	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-000i-9000000000-2e16e9d6f9b3c2688f8a	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-0a4i-9000000000-9857daa028fb3016a7e2	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-0006-0009200000-0617acd25c69bf24ad1f	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-0a4i-0900000000-823dfcf6229956372e31	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-0a4i-9000000000-eec63565f8a9fe4bd336	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-000i-9000000000-008412efd202c202d56a	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-0002-0930000000-932aedc4efb5e1dd5e7b	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-0w29-0951000000-cd0895e475dd50e4934d	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-00di-9000000000-15294ba22b153cf5ab5b	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-014i-9000000000-48c370acff657443f0e6	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-0udi-0190000000-1bad10ba7388ce0c2249	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-0ue9-0792100000-9f2bfe40e4c01044d209	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-00di-9000000000-dfa7aca58cc28303ebc7	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-0udi-0900000000-282f31d8021649afdbe8	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-0udi-0290000000-eeee98e6b0514b08cd63	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Negative	splash10-0udi-1900000000-ed66566e27a94ee99f13	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Negative	splash10-00di-9100000000-b9f6b4b6ee7c88a9c569	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Negative	splash10-00di-9000000000-929aea63ace0e20c6d43	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Negative	splash10-00di-9000000000-ba9cd5b3e37ded5d3764	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Positive	splash10-0a4i-6900000000-5622633ab0a27d2e5360	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Positive	splash10-03di-9000000000-3e25ca80e2e62be19ac5	Spectrum
MS	Mass Spectrum (Electron Ionization)	splash10-0200-9000000000-dc5e2afcfab602641180	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
2D NMR	[1H,1H] 2D NMR Spectrum	Not Available	Spectrum
2D NMR	[1H,13C] 2D NMR Spectrum	Not Available	Spectrum

Biological Properties

Cellular Locations

Not Available

Biofluid Locations and Tissue Locations

Cerebrospinal Fluid (CSF)
Colostrum
Embryo culture media
Feces
Follicular Fluid
Kidney
Lung
Meat
Milk
Plasma
Ruminal Fluid
Serum
Synovial Fluid
Urine

Concentrations

Biofluid	Status	Value	Condition	Species	Reference	Details
Cerebrospinal Fluid (CSF)	Detected but not Quantified	Not Applicable	Not Available	Ovine	17510975	details
Colostrum	Detected but not Quantified	Not Applicable	Not Available	Bovine	22361340	details
Colostrum	Detected but not Quantified	Not Applicable	Not Available	Bovine	22417363	details
Embryo culture media	Detected but not Quantified	Not Applicable	Not Available	Bovine	20058302	details
Embryo culture media	Detected but not Quantified	Not Applicable	Not Available	Bovine	20058302	details
Feces	Detected but not Quantified	Not Applicable	Not Available	Ovine	17249687	details
Feces	Detected but not Quantified	Not Applicable	Not Available	Equine	E. E. Escalona, J...	details
Follicular Fluid	Detected and Quantified	120 +/- 10-160+/-0 uM	Not Available	Porcine	183842	details
Kidney	Detected but not Quantified	Not Applicable	Not Available	Porcine	21761043	details
Lung	Detected but not Quantified	Not Applicable	Not Available	Porcine	23412987	details
Meat	Detected but not Quantified	Not Applicable	Not Available	Bovine	22361340	details
Meat	Detected but not Quantified	Not Applicable	Not Available	Bovine	22417363	details
Milk	Detected but not Quantified	Not Applicable	Not Available	Bovine	25108860	details
Plasma	Detected and Quantified	148 +/- 3-159+/-8 uM	Not Available	Porcine	22513987	details
Plasma	Detected and Quantified	424 +/- 18-450+/-65 uM	Not Available	Porcine	22513987	details
Plasma	Detected and Quantified	478 +/- 49-347+/-35 uM	Not Available	Porcine	22513987	details
Plasma	Detected and Quantified	58.4 uM	Not Available	Bovine	17197001	details
Plasma	Detected and Quantified	61.5 uM	Not Available	Bovine	17197001	details
Plasma	Detected and Quantified	66.7 uM	Not Available	Bovine	17197001	details
Plasma	Detected and Quantified	72.0-112.3 uM	Not Available	Ovine	17900638	details
Plasma	Detected and Quantified	80.0 +/- 20.8 uM	Not Available	Ovine	17900638	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Bovine	24630653	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Ovine	17249687	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Ovine	22242129	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Porcine	22675387	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Bovine	24070026	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Porcine	20231903	details
Plasma	Detected and Quantified	130.32 uM	Not Available	Porcine	25820777	details
Plasma	Detected and Quantified	146.02 uM	Not Available	Porcine	25820777	details
Plasma	Detected and Quantified	148.99 uM	Not Available	Porcine	25820777	details
Plasma	Detected and Quantified	170.2 uM	Not Available	Porcine	25820777	details
Ruminal Fluid	Detected and Quantified	123 +/- 57 uM	Not Available	Bovine	Saleem F, Bouatra...	details
Ruminal Fluid	Detected and Quantified	49 +/- 25 uM	Not Available	Bovine	Saleem F, Bouatra...	details
Ruminal Fluid	Detected and Quantified	49 +/- 25 uM	Not Available	Bovine	Saleem F, Bouatra...	details
Ruminal Fluid	Detected and Quantified	50 +/- 14 uM	Not Available	Bovine	Saleem F, Bouatra...	details
Ruminal Fluid	Detected and Quantified	85 +/- 29 uM	Not Available	Bovine	Saleem F, Bouatra...	details
Ruminal Fluid	Detected but not Quantified	Not Applicable	Not Available	Bovine	Fozia Saleem, Sou...	details
Serum	Detected and Quantified	77.9116 +/- 19.264 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	95.3831 +/- 27.8633 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	69.1625 +/- 18.4306 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	176.4 uM	Not Available	Porcine	Barbara U. Metzle...	details
Serum	Detected and Quantified	85.4119 +/- 40.6463 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	216.4 uM	Not Available	Porcine	Barbara U. Metzle...	details
Serum	Detected and Quantified	232.8 uM	Not Available	Porcine	Barbara U. Metzle...	details
Serum	Detected and Quantified	250.3 uM	Not Available	Porcine	Barbara U. Metzle...	details
Serum	Detected and Quantified	59.69 +/- 22.08 uM	Not Available	Ovine	Candidate serum m...	details
Serum	Detected and Quantified	70.8131 +/- 27.6125 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	85.005 +/- 44.5437 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	56.9293 +/- 9.9572 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	90.823 +/- 41.9471 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	108 uM	Not Available	Porcine	26020888	details
Serum	Detected and Quantified	82.594 uM	Not Available	Porcine	26020888	details
Serum	Detected and Quantified	83.545 uM	Not Available	Porcine	26020888	details
Serum	Detected and Quantified	120.275 uM	Not Available	Porcine	26020888	details
Serum	Detected and Quantified	74.2919 +/- 24.3682 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	76.9167 +/- 34.6393 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	101.3859 +/- 48.4164 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Porcine	23255817	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Bovine	25372282	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Bovine	25372282	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Bovine	25372282	details
Serum	Detected and Quantified	86.0713 +/- 31.5363 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	78.9266 +/- 33.6965 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	130 +/- 10 uM	Not Available	Porcine	183842	details
Serum	Detected and Quantified	83.9399 +/- 34.2627 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	64.5691 +/- 16.7731 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	77.7974 +/- 23.844 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	97.3293 +/- 54.9106 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	58.3827 +/- 16.962 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	78.1192 +/- 40.1132 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	81.9694 +/- 41.3794 uM	Normal	Ovine	Goldansaz et al.,...	details
Synovial Fluid	Detected but not Quantified	Not Applicable	Not Available	Ovine	25283885	details
Urine	Detected but not Quantified	Not Applicable	Not Available	Equine	E. E. Escalona, J...	details

External Links

DrugBank ID

DB00133

HMDB ID

HMDB0000187

FooDB ID

FDB012739

Phenol Explorer ID

Not Available

KNApSAcK ID

BiGG ID

BioCyc ID

METLIN ID

PDB ID

Not Available

Wikipedia Link

Chemspider ID

ChEBI ID

PubChem Compound ID

Kegg Compound ID

YMDB ID

ECMDB ID

References

Synthesis Reference

Not Available

Material Safety Data Sheet (MSDS)

Not Available

General References

de Koning TJ, Snell K, Duran M, Berger R, Poll-The BT, Surtees R: L-serine in disease and development. Biochem J. 2003 May 1;371(Pt 3):653-61. [12534373 ]

Showing metabocard for L-Serine (LMDB00083)

Structure for LMDB00083 (L-Serine)