Livestock Metabolome Database: Showing metabocard for L-Threonine (LMDB00074)

Identification Taxonomy Ontology Physical properties Spectra Biological properties Concentrations Links References XML

Record Information

Version

1.0

Creation Date

2016-07-13 19:41:48 UTC

Update Date

2021-04-30 20:57:58 UTC

Lmdb

LMDB00074

Secondary Accession Numbers

None

Metabolite Identification

Common Name

L-Threonine

Description

Threonine is an essential amino acid in animals. It is abundant in animal plasma, particularly in newborns. Severe deficiency of threonine causes neurological dysfunction and lameness in experimental animals. Threonine is an immunostimulant which promotes the growth of thymus gland. It also can probably promote cell immune defense function. This amino acid has been useful in the treatment of genetic spasticity disorders and multiple sclerosis at a dose of 1 gram daily. It is highly concentrated in meat products, cottage cheese and wheat germ. (http://www.dcnutrition.com/AminoAcids/) The threonine content of most of the infant formulas currently on the market is approximately 20% higher than the threonine concentration in animal milk. Due to this high threonine content the plasma threonine concentrations are up to twice as high in premature infants fed these formulas than in infants fed animal milk. The whey proteins which are used for infant formulas are sweet whey proteins. Sweet whey results from cheese production. Threonine catabolism in mammals appears to be due primarily (70-80%) to the activity of threonine dehydrogenase (EC 1.1.1.103) that oxidizes threonine to 2-amino-3-oxobutyrate, which forms glycine and acetyl CoA, whereas threonine dehydratase (EC 4.2.1.16) that catabolizes threonine into 2-oxobutyrate and ammonia, is significantly less active. Increasing the threonine plasma concentrations leads to accumulation of threonine and glycine in the brain. Such accumulation affects the neurotransmitter balance which may have consequences for the brain development during early postnatal life. Thus, excessive threonine intake during infant feeding should be avoided. (PMID 9853925 ).

Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
(2S)-Threonine	ChEBI
(2S,3R)-(-)-Threonine	ChEBI
(2S,3R)-2-Amino-3-hydroxybutanoic acid	ChEBI
2-Amino-3-hydroxybutyric acid	ChEBI
L-(-)-Threonine	ChEBI
L-2-Amino-3-hydroxybutyric acid	ChEBI
L-alpha-Amino-beta-hydroxybutyric acid	ChEBI
L-Threonin	ChEBI
T	ChEBI
Thr	ChEBI
THREONINE	ChEBI
(2S,3R)-2-Amino-3-hydroxybutanoate	Generator
2-Amino-3-hydroxybutyrate	Generator
L-2-Amino-3-hydroxybutyrate	Generator
L-a-Amino-b-hydroxybutyrate	Generator
L-a-Amino-b-hydroxybutyric acid	Generator
L-alpha-Amino-beta-hydroxybutyrate	Generator
L-Α-amino-β-hydroxybutyrate	Generator
L-Α-amino-β-hydroxybutyric acid	Generator
(2S,3R)-2-Amino-3-hydroxybutyrate	HMDB
(2S,3R)-2-Amino-3-hydroxybutyric acid	HMDB
(R-(R,s))-2-amino-3-hydroxybutanoate	HMDB
(R-(R,s))-2-amino-3-hydroxybutanoic acid	HMDB
(S)-Threonine	HMDB
2-Amino-3-hydroxybutanoate	HMDB
2-Amino-3-hydroxybutanoic acid	HMDB
Threonin	HMDB
[R-(R,s)]-2-amino-3-hydroxy-butanoate	HMDB
[R-(R,s)]-2-amino-3-hydroxy-butanoic acid	HMDB
[R-(R,s)]-2-amino-3-hydroxybutanoate	HMDB
[R-(R,s)]-2-amino-3-hydroxybutanoic acid	HMDB
L Threonine	HMDB

Chemical Formula

C₄H₉NO₃

Average Molecular Weight

119.1192

Monoisotopic Molecular Weight

119.058243159

IUPAC Name

(2S,3R)-2-amino-3-hydroxybutanoic acid

Traditional Name

L-threonine

CAS Registry Number

72-19-5

SMILES

C[C@@H](O)[C@H](N)C(O)=O

InChI Identifier

InChI=1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1

InChI Key

AYFVYJQAPQTCCC-GBXIJSLDSA-N

Chemical Taxonomy

Description

belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.

Kingdom

Organic compounds

Super Class

Organic acids and derivatives

Class

Carboxylic acids and derivatives

Sub Class

Amino acids, peptides, and analogues

Direct Parent

L-alpha-amino acids

Alternative Parents

Substituents

L-alpha-amino acid
Beta-hydroxy acid
Short-chain hydroxy acid
Hydroxy acid
Fatty acid
Amino acid
Secondary alcohol
Carboxylic acid
Monocarboxylic acid or derivatives
Alcohol
Hydrocarbon derivative
Primary amine
Organooxygen compound
Organonitrogen compound
Organic oxide
Primary aliphatic amine
Organopnictogen compound
Organic oxygen compound
Carbonyl group
Organic nitrogen compound
Amine
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

aspartate family amino acid (CHEBI:16857 )
proteinogenic amino acid (CHEBI:16857 )
L-alpha-amino acid (CHEBI:16857 )
threonine (CHEBI:16857 )
Common amino acids (C00188 )

Ontology

Status

Detected and Quantified

Origin

Not Available

Biofunction

Not Available

Application

Not Available

Cellular locations

Not Available

Physical Properties

State

Not Available

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	-3	ALOGPS
logP	-3.5	ChemAxon
logS	0.6	ALOGPS
pKa (Strongest Acidic)	2.21	ChemAxon
pKa (Strongest Basic)	9	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	4	ChemAxon
Hydrogen Donor Count	3	ChemAxon
Polar Surface Area	83.55 Å²	ChemAxon
Rotatable Bond Count	2	ChemAxon
Refractivity	26.46 m³·mol⁻¹	ChemAxon
Polarizability	11.08 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	Yes	ChemAxon
MDDR-like Rule	Yes	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	View
GC-MS	GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS)	splash10-0gb9-0930000000-045341234639d940688b	Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (Non-derivatized)	splash10-0gb9-0930000000-08f448150a2533471625	Spectrum
GC-MS	GC-MS Spectrum - GC-MS (2 TMS)	splash10-0159-1910000000-98a39d63665a1a1855dd	Spectrum
GC-MS	GC-MS Spectrum - GC-MS (3 TMS)	splash10-014i-1960000000-82e1bd8ff2e302e6b51b	Spectrum
GC-MS	GC-MS Spectrum - EI-B (Non-derivatized)	splash10-0159-0910000000-d36a7a07f0444e55e38f	Spectrum
GC-MS	GC-MS Spectrum - EI-B (Non-derivatized)	splash10-014i-0980000000-ebba7965f95f804648ab	Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Non-derivatized)	splash10-0gb9-0930000000-045341234639d940688b	Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Non-derivatized)	splash10-0gb9-0930000000-08f448150a2533471625	Spectrum
GC-MS	GC-MS Spectrum - GC-EI-QQ (Non-derivatized)	splash10-0ffa-3921000000-05359581d7eb97866c8f	Spectrum
GC-MS	GC-MS Spectrum - GC-MS (Non-derivatized)	splash10-0159-1910000000-98a39d63665a1a1855dd	Spectrum
GC-MS	GC-MS Spectrum - GC-MS (Non-derivatized)	splash10-014i-1960000000-82e1bd8ff2e302e6b51b	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	splash10-00dl-9000000000-a05d200d324c3242c239	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (2 TMS) - 70eV, Positive	splash10-0fdk-8930000000-c4701f28963821b700b3	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TMS_1_1) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TMS_1_2) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TMS_1_3) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TMS_2_2) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TMS_2_3) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TMS_2_4) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TBDMS_1_1) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TBDMS_1_2) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TBDMS_1_3) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TBDMS_2_1) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TBDMS_2_2) - 70eV, Positive	Not Available	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)	splash10-00di-9300000000-85dce837b0f965e73c8a	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)	splash10-0a4i-9000000000-221510fd551c0b52c362	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)	splash10-0a4i-9100000000-6ee11649899572cd4867	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-00di-0900000000-fde7ef1951fddff4b817	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-0uk9-8900000000-2d7e5609618437e59272	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-000i-9000000000-4b43567f4a446aed0828	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-014i-4900000000-45382d9abd25be948e5b	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-00di-0900000000-071b61d3ea723715c1c1	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-0a59-9000000000-c8320d0556dbe72049ca	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-0uk9-8900000000-9945ecd06408cb733177	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-0ufr-8900000000-c9804e2bfc51ec0e8593	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-02t9-0692200000-f96dba3c74726ede32de	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-00di-9000000000-94eeca12e76e23c1695e	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-014i-0930000000-efff9b10ae39f6ce6095	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-014i-0190000000-74ab3cba7b57b1b1b681	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Negative	splash10-014i-1900000000-d9348197a5df9756d30c	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Negative	splash10-00di-9100000000-9008bb1dfd2806e9f87d	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Negative	splash10-00di-9000000000-47fd01696817c86aecc5	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Negative	splash10-00di-9000000000-ba9cd5b3e37ded5d3764	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Positive	splash10-00di-1900000000-3fa8bd5efd825e5ac3fa	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Positive	splash10-0kn9-9200000000-063cffd047551fca9ee6	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Positive	splash10-0a4i-9000000000-8b82bffd35f30875a7c0	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Positive	splash10-0a4i-9000000000-1748dd9a759c98e1c5ee	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Positive	splash10-0a4i-9000000000-e9069de219196460cc61	Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-0uk9-6900000000-d30fcc60bda11aeb88b4	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
2D NMR	[1H,1H] 2D NMR Spectrum	Not Available	Spectrum
2D NMR	[1H,13C] 2D NMR Spectrum	Not Available	Spectrum

Biological Properties

Cellular Locations

Not Available

Biofluid Locations and Tissue Locations

Cerebrospinal Fluid (CSF)
Colostrum
Embryo culture media
Feces
Follicular Fluid
Kidney
Liver
Lung
Meat
Milk
Plasma
Ruminal Fluid
Serum
Urine

Concentrations

Biofluid	Status	Value	Condition	Species	Reference	Details
Cerebrospinal Fluid (CSF)	Detected but not Quantified	Not Applicable	Not Available	Ovine	17510975	details
Colostrum	Detected but not Quantified	Not Applicable	Not Available	Bovine	S. F. Graham, T. ...	details
Colostrum	Detected but not Quantified	Not Applicable	Not Available	Bovine	25637742	details
Colostrum	Detected but not Quantified	Not Applicable	Not Available	Bovine	22361340	details
Colostrum	Detected but not Quantified	Not Applicable	Not Available	Bovine	22417363	details
Embryo culture media	Detected but not Quantified	Not Applicable	Not Available	Bovine	20058302	details
Embryo culture media	Detected but not Quantified	Not Applicable	Not Available	Bovine	20058302	details
Feces	Detected but not Quantified	Not Applicable	Not Available	Ovine	17249687	details
Feces	Detected but not Quantified	Not Applicable	Not Available	Equine	E. E. Escalona, J...	details
Follicular Fluid	Detected and Quantified	160 +/- 10-210+/-0 uM	Not Available	Porcine	183842	details
Kidney	Detected but not Quantified	Not Applicable	Not Available	Porcine	21761043	details
Liver	Detected but not Quantified	Not Applicable	Not Available	Porcine	21761043	details
Lung	Detected but not Quantified	Not Applicable	Not Available	Porcine	23412987	details
Meat	Detected and Quantified	0.57+/-0.28 umol/g	Not Available	Bovine	S. F. Graham, T. ...	details
Meat	Detected and Quantified	0.64+/-0.27 umol/g	Not Available	Bovine	S. F. Graham, T. ...	details
Meat	Detected and Quantified	0.69+/-0.27 umol/g	Not Available	Bovine	S. F. Graham, T. ...	details
Meat	Detected and Quantified	0.69+/-0.31 umol/g	Not Available	Bovine	S. F. Graham, T. ...	details
Meat	Detected but not Quantified	Not Applicable	Not Available	Bovine	S. F. Graham, T. ...	details
Meat	Detected but not Quantified	Not Applicable	Not Available	Bovine	25637742	details
Meat	Detected but not Quantified	Not Applicable	Not Available	Bovine	22361340	details
Meat	Detected but not Quantified	Not Applicable	Not Available	Bovine	22417363	details
Milk	Detected and Quantified	1-46 uM	Not Available	Bovine	20338431	details
Milk	Detected but not Quantified	Not Applicable	Not Available	Bovine	Kurt J. Boudonck,...	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Ovine	17249687	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Ovine	22242129	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Porcine	22675387	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Porcine	20231903	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Equine	21496096	details
Plasma	Detected and Quantified	121 +/- 1-143+/-13 uM	Not Available	Porcine	22513987	details
Plasma	Detected and Quantified	361 +/- 47-194+/-2 uM	Not Available	Porcine	22513987	details
Plasma	Detected and Quantified	382 +/- 34-225+/-26 uM	Not Available	Porcine	22513987	details
Plasma	Detected and Quantified	39.9 uM	Not Available	Bovine	17197001	details
Plasma	Detected and Quantified	48.5 uM	Not Available	Bovine	17197001	details
Plasma	Detected and Quantified	51.9 uM	Not Available	Bovine	17197001	details
Plasma	Detected and Quantified	134.8 +/- 56.8 uM	Not Available	Ovine	17900638	details
Plasma	Detected and Quantified	39.4-152.9 uM	Not Available	Ovine	17900638	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Equine	E. E. Escalona, J...	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Bovine	25913299	details
Plasma	Detected and Quantified	382.39 uM	Not Available	Porcine	25820777	details
Plasma	Detected and Quantified	586.55 uM	Not Available	Porcine	25820777	details
Plasma	Detected and Quantified	662.59 uM	Not Available	Porcine	25820777	details
Plasma	Detected but not Quantified	Not Applicable	Not Available	Bovine	24630653	details
Plasma	Detected and Quantified	769.39 uM	Not Available	Porcine	25820777	details
Ruminal Fluid	Detected and Quantified	25 +/- 8 uM	Not Available	Bovine	Saleem F, Bouatra...	details
Ruminal Fluid	Detected and Quantified	25 +/- 8 uM	Not Available	Bovine	Saleem F, Bouatra...	details
Ruminal Fluid	Detected and Quantified	28 +/- 7 uM	Not Available	Bovine	Saleem F, Bouatra...	details
Ruminal Fluid	Detected and Quantified	35 +/- 22 uM	Not Available	Bovine	Saleem F, Bouatra...	details
Ruminal Fluid	Detected and Quantified	41 +/- 29 uM	Not Available	Bovine	Saleem F, Bouatra...	details
Ruminal Fluid	Detected but not Quantified	Not Applicable	Not Available	Bovine	Fozia Saleem, Sou...	details
Ruminal Fluid	Detected and Quantified	23.1 uM	Not Available	Bovine	22959937	details
Ruminal Fluid	Detected and Quantified	29.9 uM	Not Available	Bovine	22959937	details
Ruminal Fluid	Detected and Quantified	36.4 uM	Not Available	Bovine	22959937	details
Ruminal Fluid	Detected and Quantified	41.3 uM	Not Available	Bovine	22959937	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Porcine	21429726	details
Serum	Detected and Quantified	97.7121 +/- 28.7179 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Caprine	24214495	details
Serum	Detected and Quantified	123.5579 +/- 33.3655 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	80.7371 +/- 26.8447 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	109.4511 +/- 48.5943 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	102.9588 +/- 35.2307 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	209 uM	Not Available	Porcine	Barbara U. Metzle...	details
Serum	Detected and Quantified	215.4 uM	Not Available	Porcine	Barbara U. Metzle...	details
Serum	Detected and Quantified	273.06 uM	Not Available	Porcine	Barbara U. Metzle...	details
Serum	Detected and Quantified	298.5 uM	Not Available	Porcine	Barbara U. Metzle...	details
Serum	Detected and Quantified	115.7911 +/- 43.217 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	108.05 +/- 52.82 uM	Not Available	Ovine	Candidate serum m...	details
Serum	Detected and Quantified	83.4117 +/- 17.9054 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	101.4288 +/- 44.1069 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	110.6685 +/- 34.8683 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	79.0533 +/- 26.7616 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	72.7 uM	Not Available	Porcine	26020888	details
Serum	Detected and Quantified	91.00128 uM	Not Available	Porcine	26020888	details
Serum	Detected and Quantified	75.555 uM	Not Available	Porcine	26020888	details
Serum	Detected and Quantified	109.89 uM	Not Available	Porcine	26020888	details
Serum	Detected and Quantified	114.5444 +/- 40.4619 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	0.00791 +/- 0.000747 uM	Not Available	Porcine	19847666	details
Serum	Detected and Quantified	0.00613 +/- 0.000520 uM	Not Available	Porcine	19847666	details
Serum	Detected and Quantified	108.4483 +/- 36.6719 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	98.9158 +/- 42.9757 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	130 +/- 0 uM	Not Available	Porcine	183842	details
Serum	Detected and Quantified	91.6481 +/- 38.5357 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	81.3808 +/- 18.9078 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	97.4138 +/- 31.6771 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	122.0001 +/- 48.7649 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	77.2134 +/- 20.3763 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected and Quantified	112.7423 +/- 51.5145 uM	Normal	Ovine	Goldansaz et al.,...	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Porcine	21942754	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Porcine	18989615	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Porcine	23255817	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Porcine	26020888	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Porcine	22761248	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Porcine	21584308	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Bovine	25372282	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Bovine	25372282	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Bovine	25372282	details
Serum	Detected but not Quantified	Not Applicable	Not Available	Porcine	21761043	details
Serum	Detected and Quantified	119.0373 +/- 40.989 uM	Normal	Ovine	Goldansaz et al.,...	details
Urine	Detected but not Quantified	Not Applicable	Not Available	Equine	E. E. Escalona, J...	details
Urine	Detected but not Quantified	Not Applicable	Not Available	Porcine	21761043	details

External Links

DrugBank ID

DB00156

HMDB ID

HMDB0000167

FooDB ID

FDB011999

Phenol Explorer ID

Not Available

KNApSAcK ID

C00001394

BiGG ID

34186

BioCyc ID

THR

METLIN ID

PDB ID

Not Available

Wikipedia Link

Chemspider ID

ChEBI ID

PubChem Compound ID

Kegg Compound ID

YMDB ID

ECMDB ID

References

Synthesis Reference

Not Available

Material Safety Data Sheet (MSDS)

Not Available

General References

Boehm G, Cervantes H, Georgi G, Jelinek J, Sawatzki G, Wermuth B, Colombo JP: Effect of increasing dietary threonine intakes on amino acid metabolism of the central nervous system and peripheral tissues in growing rats. Pediatr Res. 1998 Dec;44(6):900-6. [9853925 ]

Showing metabocard for L-Threonine (LMDB00074)

Structure for LMDB00074 (L-Threonine)